replicateBE: Average Bioequivalence with Expanding Limits (ABEL)

Performs comparative bioavailability calculations for the EMA's Average Bioequivalence with Expanding Limits (ABEL). Implemented are 'Method A' and 'Method B', detection of outliers. If the design allows, assessment of the empiric Type I Error and iteratively adjusting alpha to control the consumer risk. Average Bioequivalence (ABE) - optionally with tighter (EMA: NTIDs) or wider limits (GCC: Cmax) - is implemented as well.

Version: 1.0.12
Depends: R (≥ 3.5.0)
Imports: readxl (≥ 1.0.0), PowerTOST (≥ 1.3.3), lmerTest, nlme, pbkrtest, graphics, grDevices
Suggests: knitr, rmarkdown, testthat, devtools
Published: 2019-11-11
Author: Helmut Schütz ORCID iD [aut, cre], Michael Tomashevskiy [ctb], Detlew Labes ORCID iD [ctb]
Maintainer: Helmut Schütz <helmut.schuetz at bebac.at>
BugReports: https://github.com/Helmut01/replicateBE/issues
License: GPL (≥ 3)
URL: https://github.com/Helmut01/replicateBE
NeedsCompilation: no
Materials: README NEWS
CRAN checks: replicateBE results

Downloads:

Reference manual: replicateBE.pdf
Vignettes: replicateBE
Package source: replicateBE_1.0.12.tar.gz
Windows binaries: r-devel: replicateBE_1.0.12.zip, r-release: replicateBE_1.0.12.zip, r-oldrel: replicateBE_1.0.12.zip
OS X binaries: r-release: replicateBE_1.0.12.tgz, r-oldrel: replicateBE_1.0.12.tgz
Old sources: replicateBE archive

Linking:

Please use the canonical form https://CRAN.R-project.org/package=replicateBE to link to this page.